BOOM is an ontology construction technique that combines deductive reasoning and probabilistic inference. It takes two or more ontologies linked by hypothetical axioms, and estimates the most likely unified logical ontology, thereby combining multiple separate ontologies into a single coherent ontology. k-BOOM is a version of BOOM that works by factorizing the probabilistic ontology into k submodules. It was used to build the Mondo merged disease ontology.

Kboom phenoday-2016 from Chris Mungall


  • Preprint: Mungall CJ, Koehler S, Robinson P, Holmes I, Haendel M. (2019). k-BOOM: A Bayesian approach to ontology structure inference, with applications in disease ontology construction. bioRxiv.